timsTOF

timsTOF Technology with 4th dimension

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timsTOF

Benefits of timsTOF

High Acquisition Speed at Ultra-High Resolution

PASEF enables MS/MS acquisition at >100 Hz, making high-throughput measurements using short gradients possible while maintaining deep proteome coverage or high protein depth measurements in less time.

Mobility Offset Mass Aligned (MOMA)

It identifies more near-isobaric peptides and post-translationally modified (PTMs) peptides per unit time. PTM-positional isomers can also be quantified.

CCS-Aware Workflows

CCS-Aware analysis software increases the confidence of identifications and quantitation, while increasing data completeness.

Increased Sensitivity

The time-focusing benefit of dual-TIMS funnel technology increases sensitivity thereby allowing for loading of lower sample amounts and simpler sample preparation techniques.

Increased Robustness

The orthogonal geometry of the inlet glass capillary to the axis of the mass analyzer combined with dual-TIMS funnel technology, greatly increases robustness, allowing for sustained MS performance over large sample cohorts, maximizing instrument uptime.

Open Data Format (*.tdf)

Open data format easily allows timsTOF data to be used in custom developed bioinformatics solutions.

Applications

Analyze isomeric compounds
Analyze isomeric compounds
High-confidence forensic screening
High-confidence forensic screening
Characterize metabolites and secondary metabolites
Characterize metabolites and secondary metabolites
True Isotopic Pattern or TIPTM
True Isotopic Pattern or TIPTM
Food and environmental research
Food and environmental research
Polymer analysis
Polymer analysis

Assays/Consumables/Software

Features

Resolution

Consistently high ion mobility resolution unravels the complexity of samples and unlocks insights that remain hidden in standard mass spectrometry

Flexibility

Adjustable ion mobility separation based on TIMS allows the exploration of samples in diverse and meaningful ways

Confidence

Boosts confidence and specificity of compound identification with an expanded set of orthogonal qualifiers that are measured with great accuracy

timsTOF

timsTOF

timsTOF Technology with 4th dimension

Enquire Now
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