Broadening the reach of mass spec both in and outside the lab.
From “ Swab and detect” one sample in seconds to a screening of thousands, DART empowers Mass spectrometry to go where it has never gone before.
Screen, identify & semi-quantify Known & Unknown targets with much more confidence
Identified Polar, a nonpolar compound in a single run
>12 min Run & Analysis time (Sample to Report)
Curated Library & Methods for over 6000+ Toxicology relevant compounds & their metabolites
New compound can be added in few clicks
UHPLC combined with true MSn and comprehensive Drug Libraries
DART Technology: A New Ionization for Rapid, Non-contact, Surface Sampling of Compounds
More Efficient
DART enables a simple workflow requiring little to NO sample prep. Just swap, spot, dip or scan and detect.
Increase Productivity
Don’t wait for answers your analysis, get your answers where and when you need it.
Save time
Analyze a single sample in seconds, to a 384 well plate in less than 25 minutes.
Pulsed Gas DART-MS for High Throughput Experimentation
DART MS Supplements Characterization Workflow
Featured Videos
Featured Applications
Forensic Toxicology Screening
Food and environmental screening
Impurity screening
An instrument for every need:
Integrated benchtop system for Research Labs
For Core Labs and High Sample Throughput
nCounter Life Science Assays:
nCounter Elements™:
Expandable with Additional Prep Station:
Enterprise Package:
PROSIGNA optional add-on:
Runs Per Day:
Throughput (Lanes Per Day):
Hands on Time:
Reaction Volume Required:
Linear Dynamic Range:
Throughput:
Yes
Yes
No
No
No
2
24
10 mins
Up to 35 µl
6 x10* total count
12 lanes/6 hours
Yes
Yes
Yes
Yes
No
4*
48-96*
15 mins
Up to 30 µl
7 x10* total count
12 lanes/2.5 hours
nCounter Sprint
nCounter Flex
Product Comparison
Assays/Consumables/Software
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UHR QTOF mass spectrometer with Full Scan MS and broadband CID (bbCID) MS/MS methods
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An Elute UHPLC system, with Bruker columns, mobile phases, and QC standard
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TASQ screening and quantitation software for rapid data processing, including ready methods for multi-target screening
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The high-quality and robust TargetScreener database including more than 3000 entries relevant for food safety, environmental protection, and toxicology research screening
UHPLC combined with true MSn and comprehensive drug libraries
Related Resources
Powerful integration:
The IR Biotyper and Bruker’s MALDI Biotyper can now be combined into a single seamless workflow. Data from the MALDI Biotyper® – which uses MALDI-TOF MS to identify microorganisms to species or genus level within a few minutes – can be imported into the IR Biotyper software, and once analyzed, the entire set of results can be exported to the laboratory’s LIMS in CSV format.
Simple Workflows for Rapid Processing
Analysis by DART-MS relies on a gas-phase ionization mechanism. Initial generation of the ionizing species is by a corona discharge with helium or nitrogen which delivers excited gas atoms that, upon their release into the atmosphere, initiates a cascade of gas-phase reactions. This results in reagent ions created from atmospheric water or (solvent) vapor in the vicinity of the surface subject to analysis where they affect a chemical ionization process. DART ionization processes can generate positive or negative ions, predominantly even-electron specie
Comprehensive Solutions for Every Workflow
Direct analysis in real-time mass spectrometry (DART-MS) is an established technique for rapid mass spectral analysis of a large variety of samples. It analyzes the sample at atmospheric pressure. It can be applied to compounds that have been deposited or adsorbed onto surfaces or that are being desorbed into the atmosphere. The combination of the DART ionization source and interface can be customized in multiple geometries and with various accessories to adapt the setup as required.
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