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Direct Analysis in Real Time Mass Spectrometry
DART-MS

Direct Analysis in Real Time Mass Spectrometry
DART-MS

Analyze More, Faster

Enquire Now
Broadening the reach of mass spec both in and outside the lab.
Broadening the reach of mass spec both in and outside the lab.

From “ Swab and detect” one sample in seconds to a screening of thousands, DART empowers Mass spectrometry to go where it has never gone before.

Screen, identify & semi-quantify Known & Unknown targets with much more confidence

Identified Polar, a nonpolar compound in a single run

>12 min Run & Analysis time (Sample to Report)

Curated Library & Methods for over 6000+ Toxicology relevant compounds & their metabolites

 

New compound can be added in few clicks

UHPLC combined with true MSn and comprehensive Drug Libraries

DART Technology: A New Ionization for Rapid, Non-contact, Surface Sampling of Compounds

More Efficient

More Efficient

DART enables a simple workflow requiring little to NO sample prep. Just swap, spot, dip or scan and detect.

Increase Productivity

Increase Productivity

Don’t wait for answers your analysis, get your answers where and when you need it.

Save time

Save time

Analyze a single sample in seconds, to a 384 well plate in less than 25 minutes.

Pulsed Gas DART-MS for High Throughput Experimentation
DART MS Supplements Characterization Workflow

Featured Videos

Featured Applications

Forensic Toxicology Screening
Forensic Toxicology Screening
Food and environmental screening
Food and environmental screening
Impurity screening
Impurity screening

An instrument for every need:

Integrated benchtop system for Research Labs

For Core Labs and High Sample Throughput

nCounter Life Science Assays:

nCounter Elements™:

Expandable with Additional Prep Station:

Enterprise Package:

PROSIGNA optional add-on:

Runs Per Day:

Throughput (Lanes Per Day):

Hands on Time:

Reaction Volume Required:

Linear Dynamic Range:

Throughput:

Yes

Yes

No

No

No

2

24

10 mins

Up to 35 µl

6 x10* total count

12 lanes/6 hours

Yes

Yes

Yes

Yes

No

4*

48-96*

15 mins

Up to 30 µl

7 x10* total count

12 lanes/2.5 hours

nCounter Sprint
nCounter Flex

Product Comparison

Assays/Consumables/Software

  • UHR QTOF mass spectrometer with Full Scan MS and broadband CID (bbCID) MS/MS methods

  • An Elute UHPLC system, with Bruker columns, mobile phases, and QC standard

  • TASQ screening and quantitation software for rapid data processing, including ready methods for multi-target screening

  • The high-quality and robust TargetScreener database including more than 3000 entries relevant for food safety, environmental protection, and toxicology research screening

UHPLC combined with true MSn and comprehensive drug libraries

Related Resources

Powerful integration:

The IR Biotyper and Bruker’s MALDI Biotyper can now be combined into a single seamless workflow. Data from the MALDI Biotyper® – which uses MALDI-TOF MS to identify microorganisms to species or genus level within a few minutes – can be imported into the IR Biotyper software, and once analyzed, the entire set of results can be exported to the laboratory’s LIMS in CSV format.

Simple Workflows for Rapid Processing

iST Kit for Rapid Protein Sample Preparation

Analysis by DART-MS relies on a gas-phase ionization mechanism. Initial generation of the ionizing species is by a corona discharge with helium or nitrogen which delivers excited gas atoms that, upon their release into the atmosphere, initiates a cascade of gas-phase reactions. This results in reagent ions created from atmospheric water or (solvent) vapor in the vicinity of the surface subject to analysis where they affect a chemical ionization process. DART ionization processes can generate positive or negative ions, predominantly even-electron specie

Comprehensive Solutions for Every Workflow

Direct analysis in real-time mass spectrometry (DART-MS) is an established technique for rapid mass spectral analysis of a large variety of samples. It analyzes the sample at atmospheric pressure. It can be applied to compounds that have been deposited or adsorbed onto surfaces or that are being desorbed into the atmosphere. The combination of the DART ionization source and interface can be customized in multiple geometries and with various accessories to adapt the setup as required.

Direct Analysis in Real Time Mass Spectrometry
DART-MS

Direct Analysis in Real Time Mass Spectrometry
DART-MS

Analyze More, Faster

Enquire Now
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