LightBench Detect

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Benefits of LightBench Detect

Liquid Biopsy

Studies show there is a specific size discrepancy between the cell free DNA that comes off of a tumour versus the cell free DNA that comes off of healthy cells. Using Ranger® Technology gel-size selection, the LightBench® may be used to enhance cfDNA detection. LightBench® using Ranger® Technology can provide a better outcome for patients by reducing sequencing noise to combat false-positive results. New research has shown that the cost of determining genetic conditions through sequencing can be improved through gel size selection that looks to recover cfDNA from non-normal tissues while excluding that from healthy, normal cells.

NGS library QC

Powered by Ranger Technology, the LightBench® allows you to automate the process of electrophoresis, supporting optimisation of your research NGS workflows by enabling you to sequence more of the DNA you really care in record time. The core size selection LightBench® functionality is complemented by the ability to perform fragment length analysis and fluorescence assays for full NGS quality control assessment

Small Nucleic Acid Work

The operating principle behind Ranger® Technology was developed with the intent of recovering small nucleic acids whilst confidently rejecting adaptermers that were close in size to the target. Work with microRNA-SEQ experiments greatly benefits from size selection, which can be accurately conducted at any scale with Ranger® Technology.

Applications

Assays/Consumables/Software

Save your money and footprint on capex equipment

CfDNA analysis

Studies show there is a specific size discrepancy between the cell free DNA that comes off of a tumour versus the cell free DNA that comes off of healthy cells. Using Ranger® Technology gel-size selection, the LightBench® can be used to enhance cfDNA detection.

High recovery yield and reproducibility

Industry-leading average recovery yield of >70% and >97% reproducibility

Reduce Cost

Reduce overall spend on BCT ~10x fold by using of EDTA blood collection tubes (BCTs) instead of Streck BCTs.

Uniform and Precise Results

Independent lane voltage automatically to give a more uniform result & 30mm gel results in a distinctive sharp cut-off in size selection for a more precise result

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3 in 1 platform for DNA & RNA quantification, fragment length analysis and size selection, making it the only instrument that enables laboratories to consider the use of EDTA blood collection tubes (BCTs) instead of Streck BCTs. Reduce overall workflow costs and improve patient outcomes.

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