Food and Environmental Toxicology
The term ‘Environment’ is defined as physical surroundings and conditions, especially those affecting living organisms in the biosphere. However, all human activities are not environmentally friendly, and our synthetic methodologies generate substances that are highly toxic to human health and the environment.
Environmental toxicology deals with the sources, transport, degradation, bio-concentration in the environment, and adverse effects on humans and other desirable species of a variety of toxicants that reach their vital tissues via air, water, food additives, pesticides, and other chemicals, often at low levels but with long term adverse effects. A toxic chemical can exist in the environment in several different forms. For example, in the aquatic environment, a chemical can exist in three different forms, which in turn affect its bioavailability. These are dissolved, adsorbed to an abiotic or biotic component, suspended in the aquatic system, or deposited on the bottom material, and incorporated or accumulated in the tissues of animals and plants.
Let your food and environment be your MEDICINE not to be a TOXIN
Many investigations of environmental or food contamination have the same basic question: what has changed within place and time? This could be food production at a different location, food processing at different places, or a river polluted at different points on its water course, changing during a time period with different components (pollutants).
Screening of pesticides residues and their metabolites in environmental samples
Nowadays, simultaneous analysis of hundreds of pesticides from different classes is required, and most preferably in just one run. Although triple quadrupole (LC-QqQ-MS/MS) is the workhorse for target quantitative.
Identification of pollutants in river water
The passive sampling device allows the end user to obtain a more representative picture of pollutants that may be present in the aquatic environment than other sampling techniques. TASQ allows rapid screening and quantitation of ‘known unknowns’. workhorse for target quantitative analysis, it presents certain limitations, which can be overcome by high-resolution mass spectrometry.
Case Study
Mass spectrometry is a powerful way of analyzing unknown or targeted pesticides or monitoring emerging contaminants via untargeted or unknown screening in water.
Related Applications
TargetScreener HR
Analyzing complex body fluids for the presence of drugs and/or toxicants together with their associated metabolites is a challenging application especially when ‘getting it right the first time’ is of major importance.
TargetScreener HR is designed to meet these challenges and either accurately report which drugs/toxicants are present in the sample, or if no matches are found in the database, then provide several key pieces of analytical data and information to give the best chance of elucidating an identification.
Our Solution
IMPACT-VIP
impact™ II VIP high-resolution QTOF mass spectrometer with the novel VIP-HESI source, delivering ultimate sensitivity for comprehensive screening and quantitation tasks. Building on the proven reliability of the impact QTOF series, new technical innovations further enhance the sensitivity of the impact II VIP in Full-Sensitivity High-Resolution mode with no compromise in high-performance mass resolution, sensitivity, and dynamic range.
DART MS
Direct Analysis in Real Time Mass Spectrometry (DART-MS) is a technique used for environmental analysis. It is a rapid and versatile method that allows for the direct analysis of solid, liquid, and gas samples without the need for extensive sample preparation. DART-MS is particularly useful for the screening and identification of various environmental contaminants, pollutants, and volatile organic compounds (VOCs).
