Real-time hospital hygiene control with rapid strain typing, to combat microorganism outbreaks
Effective hospital hygiene management and microbial typing are essential for outbreak detection and preventing the spread of infections. With the IR Biotyper® microbial strain typing is now fast, easy, and economical, allowing for real-time epidemiology.
Screen, identify & semi-quantify Known & Unknown targets with much more confidence
Identified Polar, a nonpolar compound in a single run
>12 min Run & Analysis time (Sample to Report)
Curated Library & Methods for over 6000+ Toxicology relevant compounds & their metabolites
New compound can be added in few clicks
UHPLC combined with true MSn and comprehensive Drug Libraries
Microbial strain typing for real-time epidemiology
Fast and easy sample preparation of up to 30 isolates within 30 minutes
IR Spectral Range
Carboxyl group in fatty acids (and lipids) vibrates at 2800–3000 cm–1, the amide group in proteins vibrates at 1500–1800 cm–1, and the carboxy group in polysaccharides vibrates at 900–1200 cm–1.
Predefined isolate classification, based on (ANN and/or SVM) models, also supports the creation of customized strain typing methods for use in future classification experiments.
Bruker IR Biotyper® - 𝗛𝗼𝘀𝗽𝗶𝘁𝗮𝗹
Bruker IR Biotyper® - 𝗜𝗻𝗱𝘂𝘀𝘁𝗿𝘆
An instrument for every need:
Integrated benchtop system for Research Labs
For Core Labs and High Sample Throughput
nCounter Life Science Assays:
Expandable with Additional Prep Station:
PROSIGNA optional add-on:
Runs Per Day:
Throughput (Lanes Per Day):
Hands on Time:
Reaction Volume Required:
Linear Dynamic Range:
Up to 35 µl
6 x10* total count
12 lanes/6 hours
Up to 30 µl
7 x10* total count
12 lanes/2.5 hours
UHR QTOF mass spectrometer with Full Scan MS and broadband CID (bbCID) MS/MS methods
An Elute UHPLC system, with Bruker columns, mobile phases, and QC standard
TASQ screening and quantitation software for rapid data processing, including ready methods for multi-target screening
The high-quality and robust TargetScreener database including more than 3000 entries relevant for food safety, environmental protection, and toxicology research screening
UHPLC combined with true MSn and comprehensive drug libraries
The IR Biotyper and Bruker’s MALDI Biotyper can now be combined into a single seamless workflow. Data from the MALDI Biotyper® – which uses MALDI-TOF MS to identify microorganisms to species or genus level within a few minutes – can be imported into the IR Biotyper software, and once analyzed, the entire set of results can be exported to the laboratory’s LIMS in CSV format.
Simple Workflows for Rapid Processing
Analysis by DART-MS relies on a gas-phase ionization mechanism. Initial generation of the ionizing species is by a corona discharge with helium or nitrogen which delivers excited gas atoms that, upon their release into the atmosphere, initiates a cascade of gas-phase reactions. This results in reagent ions created from atmospheric water or (solvent) vapor in the vicinity of the surface subject to analysis where they affect a chemical ionization process. DART ionization processes can generate positive or negative ions, predominantly even-electron specie
Comprehensive Solutions for Every Workflow
Efficient microorganism strain typing is vital in healthcare settings, for infection control, epidemiological studies, and to better understand the causes of infection. Traditional strain typing technologies like pulsed-field gel electrophoresis, multi-locus sequence typing, latex agglutination, and whole-genome sequencing are time-consuming and resource-intensive, and not always readily available in every microbiological lab. Fast, easy-to-apply, and economical typing methods are in high demand in hospital hygiene management for infection control, epidemiological studies and to better understand the pathogenesis of infection. The IR Biotyper® is an infrared spectroscopy solution for subtyping of microorganisms, matching the hospital hygiene needs with excellent discriminatory power comparable to routine molecular genetic methods.
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