CleanPlex® TMB 500 Panel

CleanPlex® TMB 500 Panel

For Research Use Only. Not for use in diagnostic procedures.

Assessment of Tumor Mutational Burden using a Rapid, Amplicon-Based NGS Target Enrichment Strategy.

  • The CleanPlex® TMB 500 Panel is a targeted resequencing assay designed to enable rapid and accurate assessment of tumor mutational burden and mutation profile.

  • The panel is expertly curated using the latest research findings to target 516 genes associated with major solid tumor types and maintains >96% correlation with whole exome datasets.

  • The panel covers 1.64 Mb of genomic content (1.19 Mb exonic) and targets both single nucleotide variants (SNVs) and insertion-deletion mutations (indels).

  • Two pools of multiplex PCR primers are utilized to construct target-enriched libraries from either formalin-fixed paraffin-embedded (FFPE) DNA from tumor samples or high-quality gDNA from blood samples. Starting with just 20 ng of DNA (10 ng per primer pool), sequencing-ready libraries can be prepared using a streamlined workflow in just 6 hours, allowing samples to be sequenced on the same day.

Fast and reliable assay for measuring tumor mutational burden

Excellent Correlation with Whole Exome Sequencing

Prepare high-quality targeted NGS libraries using CleanPlex® Technology to replace the costly and time-consuming workflow of hybridization-based target enrichment

Fast, Streamlined Workflow

Generate sequencing-ready libraries in just 6 hours using a rapid, three-step protocol

Comprehensive Content

Interrogate 516 genes associated with the major solid tumor types to assess tumor mutational burden and characterize mutation profile

Specifications

SKU

Description

Pack Size

SKU
Description
Pack Size

916073

CleanPlex TMB 500 Panel

6 reactions

SKU
Description
Pack Size

916074

CleanPlex TMB 500 Panel

96 reactions

SKU
Description
Pack Size

716006

CleanPlex Dual-Indexed PCR Primers for Illumina® Set A

96 indexes, 96 reactions

SKU
Description
Pack Size

716018

CleanPlex Dual-Indexed PCR Primers for Illumina® Set B

96 indexes, 96 reactions

TMB 500 Panel
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