CleanPlex® UMI Lung Cancer Panel
For Research Use Only. Not for use in diagnostic procedures.
Detecting Low-Frequency Variants using a Targeted Amplicon Sequencing Approach And Molecular Barcodes
The CleanPlex® UMI Lung Cancer Panel is a targeted resequencing assay designed for rapid and high confident detection of ultralow frequency variants across the hotspot regions of 23 genes associated with lung cancer.
Based on CleanPlex UMI technology, this panel is specifically designed to work with cell-free DNA (cfDNA) and FFPE DNA for precise analysis of tumor DNA in liquid biopsy and tumor profiling applications.
The panel is powered by Paragon Genomics’ CleanPlex UMI Technology which incorporates novel unique molecular identifiers (UMIs) to enable correction of PCR and sequencing errors.
Starting with just 20 ng of DNA, sequencing-ready libraries can be prepared using a single-tube workflow in just 3.5 hours. Low-frequency variants below 0.5% allele frequency can be confidently detected with high specificity using just 30 ng of DNA.
Ultrafast and precise analysis of hotspots mutations in lung cancer
High-Confidence Variant Detection
Detect low-frequency variants below 0.5% allele frequency with high specificity using just 30 ng of DNA
Enhanced Error Correction
Remove PCR and sequencing errors with powerful error correction enabled by novel unique molecular identifiers (UMIs) that can distinguish the two strands of DNA.
Fast, Single-Tube Workflow
Generate high-quality molecular-barcoded and target-enriched NGS libraries in just 3.5 hours using a three-step, single-tube protocol
Relevant Gene Content
Interrogate 23 genes containing variants that are frequently mutated in lung cancer using a hotspot panel designed to work with cell-free DNA (cfDNA)
Specifications
SKU
Description
Pack Size
SKU
Description
Pack Size
916064
CleanPlex UMI Lung Cancer Panel
8 reactions
SKU
Description
Pack Size
916065
CleanPlex UMI Lung Cancer Panel
32 reactions
SKU
Description
Pack Size
916066
CleanPlex UMI Lung Cancer Panel
96 reactions
SKU
Description
Pack Size
716011 / 716012
CleanPlex Unique Dual-Indexed PCR Primers for Illumina® Set A
16 indexes, 32 / 96 reactions
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