CleanPlex® UMI Lung Cancer Panel

CleanPlex® UMI Lung Cancer Panel

For Research Use Only. Not for use in diagnostic procedures.

Detecting Low-Frequency Variants using a Targeted Amplicon Sequencing Approach And Molecular Barcodes

  • The CleanPlex® UMI Lung Cancer Panel is a targeted resequencing assay designed for rapid and high confident detection of ultralow frequency variants across the hotspot regions of 23 genes associated with lung cancer.

  • Based on CleanPlex UMI technology, this panel is specifically designed to work with cell-free DNA (cfDNA) and FFPE DNA for precise analysis of tumor DNA in liquid biopsy and tumor profiling applications.

  • The panel is powered by Paragon Genomics’ CleanPlex UMI Technology which incorporates novel unique molecular identifiers (UMIs) to enable correction of PCR and sequencing errors.

  • Starting with just 20 ng of DNA, sequencing-ready libraries can be prepared using a single-tube workflow in just 3.5 hours. Low-frequency variants below 0.5% allele frequency can be confidently detected with high specificity using just 30 ng of DNA.

Ultrafast and precise analysis of hotspots mutations in lung cancer

High-Confidence Variant Detection

Detect low-frequency variants below 0.5% allele frequency with high specificity using just 30 ng of DNA

Enhanced Error Correction

Remove PCR and sequencing errors with powerful error correction enabled by novel unique molecular identifiers (UMIs) that can distinguish the two strands of DNA.

Fast, Single-Tube Workflow

Generate high-quality molecular-barcoded and target-enriched NGS libraries in just 3.5 hours using a three-step, single-tube protocol

Relevant Gene Content

Interrogate 23 genes containing variants that are frequently mutated in lung cancer using a hotspot panel designed to work with cell-free DNA (cfDNA)

Specifications

SKU

Description

Pack Size

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SKU
Description
Pack Size

916064

CleanPlex UMI Lung Cancer Panel

8 reactions

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SKU
Description
Pack Size

916065

CleanPlex UMI Lung Cancer Panel

32 reactions

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SKU
Description
Pack Size

916066

CleanPlex UMI Lung Cancer Panel

96 reactions

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SKU
Description
Pack Size

716011 / 716012

CleanPlex Unique Dual-Indexed PCR Primers for Illumina® Set A

16 indexes, 32 / 96 reactions

UMI Lung Cancer Panel
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