CleanPlex Hereditary Cancer Panel v2

CleanPlex Hereditary Cancer Panel v2

For Research Use Only. Not for use in diagnostic procedures.

  • The CleanPlex Hereditary Cancer Panel v2 is a targeted resequencing assay designed for analyzing genes associated with an increased risk of developing hereditary cancers.

  • The panel is expertly curated using the latest research findings to target 37 genes and both single nucleotide variants (SNVs) and insertion-deletion mutations (indels).

  • Furthermore, it also detects hotspot mutations rs12516 and rs8176318 in the BRCA1 3’ UTR and structural rearrangement of exons 1-7 in MSH2 (Boland inversion).

  • This panel is specifically designed to detect inherited mutations and is not appropriate for the detection of other types of mutations in acquired cancers.

  • Starting with 20 ng of high-quality genomic DNA (10 ng per primer pool), sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours.

Fast and reliable analysis of genes associated with hereditary cancers

Up-to-date Gene Content

Interrogate 37 genes associated with cancers of the breast, ovary, uterus, skin, prostate, and gastrointestinal system, including rs12516 and rs8176318 in BRCA1 and Boland inversion in MSH2*

Fast, Streamlined Workflow

Generate sequencing-ready libraries in just 3 hours using a rapid, three-step protocol

Superb Performance

Prepare high-quality NGS libraries using CleanPlex Technology to enable efficient use of sequencing reads and reduce costs

Specifications

SKU

Description

Pack Size

SKU
Description
Pack Size

916114

CleanPlex Hereditary Cancer Panel v2

8 reactions

SKU
Description
Pack Size

916115

CleanPlex Hereditary Cancer Panel v2

96 reactions

SKU
Description
Pack Size

716005

CleanPlex Dual-Indexed PCR Primers for Illumina® Set A1

16 indexes, 16 reactions

SKU
Description
Pack Size

716006

CleanPlex Dual-Indexed PCR Primers for Illumina® Set A

96 indexes, 96 reactions

Hereditary Cancer Panel v2
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