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CleanPlex Hereditary Cancer Panel v2

CleanPlex Hereditary Cancer Panel v2

For Research Use Only. Not for use in diagnostic procedures.

  • The CleanPlex Hereditary Cancer Panel v2 is a targeted resequencing assay designed for analyzing genes associated with an increased risk of developing hereditary cancers.

  • The panel is expertly curated using the latest research findings to target 37 genes and both single nucleotide variants (SNVs) and insertion-deletion mutations (indels).

  • Furthermore, it also detects hotspot mutations rs12516 and rs8176318 in the BRCA1 3’ UTR and structural rearrangement of exons 1-7 in MSH2 (Boland inversion).

  • This panel is specifically designed to detect inherited mutations and is not appropriate for the detection of other types of mutations in acquired cancers.

  • Starting with 20 ng of high-quality genomic DNA (10 ng per primer pool), sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours.

Fast and reliable analysis of genes associated with hereditary cancers

Up-to-date Gene Content

Interrogate 37 genes associated with cancers of the breast, ovary, uterus, skin, prostate, and gastrointestinal system, including rs12516 and rs8176318 in BRCA1 and Boland inversion in MSH2*

Fast, Streamlined Workflow

Generate sequencing-ready libraries in just 3 hours using a rapid, three-step protocol

Superb Performance

Prepare high-quality NGS libraries using CleanPlex Technology to enable efficient use of sequencing reads and reduce costs

Specifications

SKU

Description

Pack Size

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SKU
Description
Pack Size

916114

CleanPlex Hereditary Cancer Panel v2

8 reactions

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SKU
Description
Pack Size

916115

CleanPlex Hereditary Cancer Panel v2

96 reactions

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SKU
Description
Pack Size

716005

CleanPlex Dual-Indexed PCR Primers for Illumina® Set A1

16 indexes, 16 reactions

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SKU
Description
Pack Size

716006

CleanPlex Dual-Indexed PCR Primers for Illumina® Set A

96 indexes, 96 reactions

Hereditary Cancer Panel v2
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